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Article

Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel.

Biophysical journal - 1 Jun 2004

Yu Kunqian, Fu Wei, Liu Hong, Luo Xiaomin, Chen Kai Xian, Ding Jianping, Shen Jianhua, Jiang Hualiang

Abstract excerpt

Based on a homology model of the Kv1.3 potassium channel, the recognitions of the six scorpion toxins, viz. agitoxin2, charybdotoxin, kaliotoxin, margatoxin, noxiustoxin, and Pandinus toxin, to the human Kv1.3 potassium channel have been investigated by using an approach of the Brownian dynamics (BD) simulation integrating molecular dynamics (MD) simulation. Reasonable three-dimensional structures of the...

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Identifiers

PMID: 15189853
DOI: 10.1529/biophysj.103.039461
PMCID: PMC1304258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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