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Article

High Throughput Sequencing of T Cell Antigen Receptors Reveals a Conserved TCR Repertoire.

Medicine - 1 Mar 2016

Hou Xianliang, Lu Chong, Chen Sisi, Xie Qian, Cui Guangying, Chen Jianing, Chen Zhi, Wu Zhongwen, Ding Yulong, Ye Ping, Dai Yong, Diao Hongyan

Abstract excerpt

The T-cell receptor (TCR) repertoire is a mirror of the human immune system that reflects processes caused by infections, cancer, autoimmunity, and aging. Next-generation sequencing has become a powerful tool for deep TCR profiling. Herein, we used this technology to study the repertoire features of TCR beta chain in the blood of healthy individuals.Peripheral blood samples were collected from 10 healthy donors....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26962778
DOI: 10.1097/MD.0000000000002839
PMCID: PMC4998859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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