Article
[Cytokine in phenotypic analysis of leukemia/lymphoma: suppression of gene expression of myeloperoxidase by IFN-gamma and subset of AML M1 defined by CD45RO+/RA-, CD7(-), CD34(-) and non-inducible HLA-DR antigen].
Rinsho byori. The Japanese journal of clinical pathology - 1 Apr 1993
Tatsumi E, Yoneda N, Kawano S, Yamaguchi N
Abstract excerpt
One of 8 to 12 pre-B ALL cells co-express CD13 and CD33 antigens, but such blasts do not express myeloperoxidase (MPO) even on electronmicroscopy or mRNA. MPO+ pre-B ALL is extremely rare (1/50-1/100), however a cell-line (Tahr87) was established in culture. In contrast, T-lineage blasts express...
Topics
- Antigens, CD
- Antigens, CD34
- Antigens, CD7
- Antigens, Differentiation, T-Lymphocyte
- Gene Expression Regulation, Leukemic
- Gene Expression Regulation, Neoplastic
- HLA-DR Antigens
- Humans
- Immunophenotyping
- Interferon-gamma
- Leukemia, Myeloid, Acute
- Leukocyte Common Antigens
- Lymphoma
- Peroxidase
- Phenotype