Article
Role of alanyl aminopeptidase in growth and function of human T cells (review).
International journal of molecular medicine - 1 Jul 1999
Lendeckel U, Arndt M, Frank K, Wex T, Ansorge S
Abstract excerpt
Alanyl aminopeptidase (APN, CD13) is highly expressed in human monocytes, and anti-CD13 monoclonal antibodies are well established routine markers in leukaemia typing. Due to activation or malignant transformation other leukocyte subpopulations including human T cells exhibit significant APN-gene and surface expression. The function of leukocyte APN is poorly understood, especially the knowledge of physiological...
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