Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.

doi:10.1111/j.1432-1033.1995.397zz.x

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Article

Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.

European journal of biochemistry - 1 Sept 1995

Antonson P, Pray M G, Jacobsson A, Xanthopoulos K G

Abstract excerpt

The product of the c-myc proto-oncogene, Myc, has been implicated in the transcriptional regulation of several genes, acting either as an activator or repressor of gene expression. To determine whether Myc is involved in the modulation of the expression of the CCAAT/enhancer-binding protein alpha (C/EBP alpha) gene, we used both stable cell lines overexpressing Myc and transient co-transfection assays. We show...

Topics

Animals
Base Sequence
Binding Sites
CCAAT-Enhancer-Binding Proteins
DNA Primers
DNA-Binding Proteins
Gene Expression Regulation
Genes, Reporter
Genes, myc
Lipoma
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Nuclear Proteins

Promoter Regions, Genetic

Transcription Factors

Transfection

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 7556187
DOI: 10.1111/j.1432-1033.1995.397zz.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7556187-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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