Article
Inhibition of transforming growth factor-beta type II receptor signaling accelerates tooth formation in mouse first branchial arch explants.
Mechanisms of development - 1 Aug 1999
Chai Y, Zhao J, Mogharei A, Xu B, Bringas P, Shuler C, Warburton D
Abstract excerpt
Members of the transforming growth factor-beta (TGF-beta) superfamily signal through their cognate receptors to determine cell phenotypes during embryogenesis. Our previous studies on the regulation of first branchial arch morphogenesis have identified critical components of a hierarchy of different TGF-beta isoforms and their possible functions in regulating tooth and cartilage formation during mandibular...
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