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Article

Chick limbs with mouse teeth: an effective in vivo culture system for tooth germ development and analysis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2003

Koyama Eiki, Wu Changshan, Shimo Tsuyoshi, Pacifici Maurizio

Abstract excerpt

Mouse tooth germ development is currently studied by three main approaches: in wild-type and mutant mouse lines, after transplantation of tooth germs to ectopic sites, and in organ culture. The in vivo approaches are the most physiological but do not provide accessibility to tooth germs for further experimental manipulation. Organ cultures, although readily accessible, do not sustain full tooth germ development...

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PMID: 12508237
DOI: 10.1002/dvdy.10217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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