Article
Propranolol disposition in Chinese subjects of different CYP2D6 genotypes.
Clinical pharmacology and therapeutics - 1 Sept 1995
Lai M L, Wang S L, Lai M D, Lin E T, Tse M, Huang J D
Abstract excerpt
Propranolol pharmacokinetics among different genotypes of CYP2D6 was compared in this study. The Chinese (Han) population consisted of 44 healthy unrelated individuals living in southern Taiwan. Endonuclease tests based on polymerase chain reaction were used to determine C/T188 genotypes of CYP2D6 in leukocyte deoxyribonucleic acid. Based on codon 188 genotypes, subjects were categorized into three groups:...
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