Propranolol disposition in Chinese subjects of different CYP2D6 genotypes.

doi:10.1016/0009-9236(95)90242-2

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Article

Propranolol disposition in Chinese subjects of different CYP2D6 genotypes.

Clinical pharmacology and therapeutics - 1 Sept 1995

Lai M L, Wang S L, Lai M D, Lin E T, Tse M, Huang J D

Abstract excerpt

Propranolol pharmacokinetics among different genotypes of CYP2D6 was compared in this study. The Chinese (Han) population consisted of 44 healthy unrelated individuals living in southern Taiwan. Endonuclease tests based on polymerase chain reaction were used to determine C/T188 genotypes of CYP2D...

Topics

Adrenergic beta-Antagonists
Adult
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Female
Genotype
Heterozygote
Homozygote
Humans
Individuality
Male
Mixed Function Oxygenases
Propranolol
Taiwan

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