Article
Osteopontin and beta 3 integrin are coordinately expressed in regenerating endothelium in vivo and stimulate Arg-Gly-Asp-dependent endothelial migration in vitro.
Circulation research - 1 Oct 1995
Liaw L, Lindner V, Schwartz S M, Chambers A F, Giachelli C M
Abstract excerpt
Osteopontin is an Arg-Gly-Asp (RGD)-containing acidic glycoprotein postulated to mediate cellular adhesion and migration in a growing number of normal and pathological conditions through interaction with integrin molecules. In this report, we have investigated the potential contributions of osteo...
Topics
- Animals
- Antigens, CD
- Base Sequence
- Cattle
- Cell Division
- Cell Movement
- Cells, Cultured
- Endothelium, Vascular
- Integrin beta3
- Male
- Molecular Sequence Data
- Mutation
- Oligopeptides
- Osteopontin
- RNA, Messenger
- Rats
- Rats, Sprague-Dawley
- Recombinant Proteins