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Article

Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments.

Matrix biology : journal of the International Society for Matrix Biology - 1 Nov 2004

Gao Yu Alice, Agnihotri Renu, Vary Calvin P H, Liaw Lucy

Abstract excerpt

Osteopontin (OPN) is a secreted, arginine-glycine-aspartic acid (RGD)-containing phosphoprotein proteolytically modified by members of the matrix metalloproteinase (MMP) family. We previously defined the MMP-3 and MMP-7 cleavage sites in OPN and found increased adhesive and migratory activity of a pool of MMP-cleaved fragments compared to full-length OPN. In the present study, we performed mutational analysis of...

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PMID: 15579312
DOI: 10.1016/j.matbio.2004.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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