Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal and Spatial Vascularization Patterns of Unions and Nonunions: Role of Vascular Endothelial Growth Factor and Bone Morphogenetic Proteins

4 Jan 2012

Abstract excerpt

BACKGROUND: Failure of fracture-healing with nonunion is a major clinical problem. Angiogenesis is closely linked to bone regeneration, but the role of angiogenesis in nonunion formation remains unclear. Because established nonunions are well vascularized, we hypothesized that lack of vascular endothelial growth factor (VEGF) expression and vascularization during the early time course of fracture-healing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone fractures and treatments
Share to Periodontal Regeneration and Treatments
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22218382
DOI: 10.2106/jbjs.j.00795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal and Spatial Vascularization Patterns of Unions and Nonunions: Role of Vascular Endothelial Growth Factor and Bone Morphogenetic ProteinsPMID 22218382Read ↗

EXPRESSION AND ACTIVATION OF THE BMP-SIGNALING COMPONENTS IN HUMAN FRACTURE NONUNIONSSemantic proximity Read ↗

Biological and molecular profile of fracture non-union tissue: A systematic review and an update on current insights.Semantic proximity Read ↗

Defective Proliferation and Osteogenic Potential with Altered Immunoregulatory phenotype of Native Bone marrow-Multipotential Stromal Cells in Atrophic Fracture Non-Union.Semantic proximity Read ↗

Fracture healing is accelerated in the absence of the adaptive immune systemSemantic proximity Read ↗

A computational model to explore the role of angiogenic impairment on endochondral ossification during fracture healing.Semantic proximity Read ↗

Levels of Expression for BMP-7 and Several BMP Antagonists May Play an Integral Role in a Fracture Nonunion: A Pilot StudySemantic proximity Read ↗

A small interfering RNA targeting Lnk accelerates bone fracture healing with early neovascularization.Semantic proximity Read ↗

Analysis of Risk Factors for Non-Union After Surgery for Limb Fractures: A Case-Control Study of 669 SubjectsSemantic proximity Read ↗

Vessel formation is induced prior to the appearance of cartilage in BMP-2-mediated heterotopic ossificationSemantic proximity Read ↗

VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture HealingSemantic proximity Read ↗

The Cell and Molecular Biology of Fracture HealingSemantic proximity Read ↗

Fgf-18 is required for osteogenesis but not angiogenesis during long bone repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.