Characterization of the trp5-27 allele used to monitor drug-induced mitotic gene conversion in the Saccharomyces cerevisiae tester strain D7.

doi:10.1093/mutage/9.4.377

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Article

Characterization of the trp5-27 allele used to monitor drug-induced mitotic gene conversion in the Saccharomyces cerevisiae tester strain D7.

Mutagenesis - 1 Jul 1994

Ehrenhofer-Murray A E, Würgler F E, Sengstag C

Abstract excerpt

Mitotic gene conversions, among other recombinagenic events, can play an important role in the multistep process of carcinogenesis. The ability of chemicals to induce such gene conversions can easily be monitored in the Saccharomyces cerevisiae tester strain YHE2, a derivative of strain D7. For t...

Topics

Alleles
Gene Conversion
Genes, Fungal
Mitosis
Mutagenicity Tests
Saccharomyces cerevisiae
Suppression, Genetic
Tryptophan Synthase

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