Article
Polymorphism of the heat-shock protein gene HSP70-2 in systemic lupus erythematosus.
British journal of rheumatology - 1 Aug 1995
Pablos J L, Carreira P E, Martín-Villa J M, Montalvo G, Arnaiz-Villena A, Gomez-Reino J J
Abstract excerpt
We investigate whether a heat-shock protein gene (HSP70-2) is involved in determining susceptibility to systemic lupus erythematosus (SLE) in a Spanish population. A HSP70-2 PstI polymorphism was characterized by restriction fragment length polymorphism analysis of polymerase chain reaction-amplified genomic DNA in 90 SLE patients and 117 controls. The PstI site containing allele (B) was significantly increased...
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