Heat shock protein 70 gene polymorphisms in rheumatoid arthritis.

doi:10.1111/j.1399-0039.1997.tb02838.x

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Article

Heat shock protein 70 gene polymorphisms in rheumatoid arthritis.

Tissue antigens - 1 Jul 1997

Vinasco J, Beraun Y, Nieto A, Fraile A, Pareja E, Mataran L, Martín J

Abstract excerpt

A role for heat shock proteins (hsp) in rheumatoid arthritis has been suggested. In addition, the specific binding of human HSP70 protein to QKRAA and RRRAA motifs within the HV3 region of disease-associated DRB1*0401 and DRB1*1001 molecules, respectively, has been proposed as being relevant to r...

Topics

Arthritis, Rheumatoid
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
HSP70 Heat-Shock Proteins
Humans
Polymorphism, Genetic
Severity of Illness Index

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