Article
HSP70 gene polymorphisms in ankylosing spondylitis.
Tissue antigens - 1 Apr 1998
Fraile A, Nieto A, Matarán L, Martín J
Abstract excerpt
Despite the strength of the association of ankylosing spondylitis (AS) with HLA-B27, other genetic elements could play a possible role in the pathophysiology of AS. Because of the localization, in the proximity of the HLA-B locus, and the involvement of heat shock proteins (HSP) in the immune response, we analyzed the influence of HSP70 gene polymorphism on the susceptibility to AS. HSP70-1, HSP70-2 and HSP70-hom...
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