A rapid method to study heat shock protein 70-2 gene polymorphism in insulin-dependent diabetes mellitus.

doi:10.1097/00006676-199610000-00009

Back to search

Article

A rapid method to study heat shock protein 70-2 gene polymorphism in insulin-dependent diabetes mellitus.

Pancreas - 1 Oct 1996

Chuang L M, Jou T S, Wu H P, Tai T Y, Lin B J

Abstract excerpt

To examine the role of DNA loci within the human leukocyte antigen (HLA) region and insulin-dependent diabetes mellitus (IDDM), we studied fine mapping of HSP70-2 gene. Polymerase chain reaction (PCR)-based genotyping was then developed and applied to type HSP70-2 in 59 patients with IDDM and 83...

Topics

Adult
Alleles
Blotting, Southern
Deoxyribonucleases, Type II Site-Specific
Diabetes Mellitus, Type 1
Gene Frequency
Genotype
HSP70 Heat-Shock Proteins
Humans
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Taiwan

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.