Article
A rapid method to study heat shock protein 70-2 gene polymorphism in insulin-dependent diabetes mellitus.
Pancreas - 1 Oct 1996
Chuang L M, Jou T S, Wu H P, Tai T Y, Lin B J
Abstract excerpt
To examine the role of DNA loci within the human leukocyte antigen (HLA) region and insulin-dependent diabetes mellitus (IDDM), we studied fine mapping of HSP70-2 gene. Polymerase chain reaction (PCR)-based genotyping was then developed and applied to type HSP70-2 in 59 patients with IDDM and 83 unrelated controls recruited from the inhabitants of northern Taiwan. Southern blot analysis revealed a diallelic PstI...
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