Article
[The heat shock protein 70-2 gene +1267(A/G) polymorphism and susceptibility to ankylosing spondylitis in Chinese Han population].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2007
Lin Jing-an, Li Wen-qing, Ye De-fu, Xue Yuan, Chen Rui-qing
Abstract excerpt
OBJECTIVE: To investigate the association between the heat shock protein 70-2 gene polymorphism and ankylosing spondylitis (AS). METHODS: The polymorphisms of HSP70-2 gene Pst I 1267 site were analysed in 176 Chinese Han AS patients and 127 healthy controls by PCR and restriction fragment length polymorphisms(RFLP) methods. RESULTS: In AS patients HSP70-2 genotypes AA, AG and GG were 46.6%, 46.0% and 7.4%...
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