Article
Lack of association between the polymorphism at the heat-shock protein (HSP70-2) gene and systemic lupus erythematosus (SLE) in the Mexican mestizo population.
Genes and immunity - 1 Aug 2000
Vargas-Alarcón G, Granados J, Martínez-Laso J, Gómez-Casado E, Zuñiga J, Salgado N, Hernández-Pacheco G, Hesiquio R, Rodríguez-Reyna T S, Gamboa R, Alcocer-Varela J, Arnaiz-Villena A
Abstract excerpt
Major histocompatibility complex (MHC) alleles have been recognized as genetic factors for developing systemic lupus erythematosus (SLE). In the present study we analyzed whether a heat-shock protein gene (HSP70-2) is involved in determining susceptibility to develop SLE in a Mexican Mestizo population. A HSP70-2 Pst I polymorphism was detected by a restriction fragment length polymorphism analysis of polymerase...
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