Article
The 8.5-kb PstI allele of the stress protein gene, Hsp70-2: an independent risk factor for systemic lupus erythematosus in African Americans?
Human immunology - 1 Jan 1996
Jarjour W, Reed A M, Gauthier J, Hunt S, Winfield J B
Abstract excerpt
SLE is dramatically more prevalent in persons of African descent than in other populations. Several genes in the class III region of the MHC have been considered as potential susceptibility loci for this disorder, but the primary association(s) remains unknown. The stress protein gene, hsp70-2, i...
Topics
- Alleles
- Base Sequence
- Black People
- Deoxyribonucleases, Type II Site-Specific
- Disease Susceptibility
- Genetic Markers
- HSP70 Heat-Shock Proteins
- Humans
- Lupus Erythematosus, Systemic
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Risk Factors
- Black or African American