Abnormal expression of the retinoblastoma gene in ovarian neoplasms and correlation to p53 and K-ras mutations.

doi:10.1006/gyno.1995.1235

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Article

Abnormal expression of the retinoblastoma gene in ovarian neoplasms and correlation to p53 and K-ras mutations.

Gynecologic oncology - 1 Sept 1995

Taylor R R, Linnoila R I, Gerardts J, Teneriello M G, Nash J D, Park R C, Birrer M J

Abstract excerpt

We analyzed the expression of the retinoblastoma (Rb) gene in a group of ovarian neoplasms previously characterized for mutations in the p53 suppressor gene and the Ki-ras oncogene. Using immunohistochemical techniques, a total of 59 ovarian neoplasms spanning the histiologic spectrum from benign...

Topics

Female
Gene Expression
Genes, ras
Humans
Immunohistochemistry
Mutation
Ovarian Neoplasms
Retinoblastoma
Staining and Labeling
Tumor Suppressor Protein p53

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