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Article

Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis.

International immunology - 1 Mar 2001

Encinas J A, Lees M B, Sobel R A, Symonowicz C, Weiner H L, Seidman C E, Seidman J G, Kuchroo V K

Abstract excerpt

Experimental autoimmune encephalomyelitis (EAE), a model for human multiple sclerosis, is an inducible inflammatory and demyelinating disease of the central nervous system (CNS). Susceptibility to this disease is heritable and is demonstrated by the development of an ascending paralysis accompanied by a loss in body wt 2-3 weeks following immunization with proteins derived from CNS myelin. In a previous genetic...

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Source

Identifiers

PMID: 11222494
DOI: 10.1093/intimm/13.3.257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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