Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

doi:10.1016/0167-5699(95)80181-2

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Article

Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

Immunology today - 1 Jun 1995

Zanelli E, Gonzalez-Gay M A, David C S

Abstract excerpt

Extensive studies in different ethnic groups have associated the susceptibility to development of rheumatoid arthritis (RA) with the third hypervariable region of the major histocompatibility complex (MHC) HLA-DR beta 1 molecule. On the basis of recent findings in the experimental mouse model of...

Topics

Alleles
Animals
Antigen Presentation
Arthritis
Arthritis, Rheumatoid
Autoimmune Diseases
Collagen
Disease Models, Animal
Disease Susceptibility
Diseases in Twins
Epitopes
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Antigens Class II
Humans

Source

Open in PubMed

Identifiers

PMID: 7544977
DOI: 10.1016/0167-5699(95)80181-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7544977-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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