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Article

Targeted expression of SV40 T antigen in the hair follicle of transgenic mice produces an aberrant hair phenotype.

Journal of cell science - 1 Mar 1995

Keough R, Powell B, Rogers G

Abstract excerpt

Directed expression of SV40 large T antigen (TAg) in transgenic mice can induce tissue-specific tumorigenesis and useful cell lines exhibiting differentiated characteristics can be established from resultant tumor cells. In an attempt to produce an immortalised mouse hair follicle cortical cell line for the study of hair keratin gene control, SV40 TAg expression was targeted to the hair follicles of transgenic...

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PMID: 7542671
DOI: 10.1242/jcs.108.3.957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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