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Article

Establishment of keratinocyte cell lines from human hair follicles

3 Sept 2018

Abstract excerpt

The advent of organotypic skin models advanced the understanding of complex mechanisms of keratinocyte differentiation. However, these models are limited by both availability of primary keratinocytes and donor variability. Keratinocytes derived from cultured hair follicles and interfollicular epidermis were immortalized by ectopic expression of SV40 and hTERT. The generated keratinocyte cell lines differentiated...

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PMID: 30194332
DOI: 10.1038/s41598-018-31829-0

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