Article
Expression of novobiocin resistance genes in the novobiocin-producing organism Streptomyces niveus.
The Journal of applied bacteriology - 1 May 1995
Hoggarth J H, Ritchie D A
Abstract excerpt
RNA isolated at intervals during fermentation from the novobiocin-producing wild-type strain of Streptomyces niveus and from a series of novobiocin-non-producing (Nov-) mutants was hybridized to DNA probes containing sequences which specify novobiocin resistance. The probes were made from inserts contained in the clones pGL101 and pGL103 which increase the level of novobiocin resistance of S. lividans...
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