Article
Expression of an heterologous gene activating actinorhodin biosynthesis in Streptomyces lividans and Streptomyces coelicolor.
FEMS microbiology letters - 1 Mar 1994
Romero N M, Parro V, Mellado R P
Abstract excerpt
Production of the blue-pigmented antibiotic actinorhodin resulted in activation in the non-producer strain Streptomyces lividans, but not in the natural producer strain Streptomyces coelicolor, when transformed with an heterologous activator gene from Streptomyces fradiae. The gene encodes a 132 nucleotide-long transcript, responsible for the actinorhodin production phenotype, and thought to act as a putative...
Topics
- Anthraquinones
- Anti-Bacterial Agents
- Base Sequence
- DNA Probes
- DNA, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Molecular Sequence Data
- Phenotype
- RNA, Antisense
- RNA, Bacterial