Article
Nucleotide sequence, mutational analysis, transcriptional start site, and product analysis of nov, the gene which affects Escherichia coli K-12 resistance to the gyrase inhibitor novobiocin.
Journal of bacteriology - 1 Apr 1995
Ivanisevic R, Milić M, Ajdić D, Rakonjac J, Savić D J
Abstract excerpt
In a previous study, we demonstrated the existence of a gene locus, nov, which affects resistance of Escherichia coli K-12 to the gyrase inhibitor novobiocin and, to a lesser degree, coumermycin (J. Rakonjac, M. Milic, D. Ajdic, D. Santos, R. Ivanisevic, and D. J. Savic, Mol. Microbiol. 6:1547-15...
Topics
- Alleles
- Base Sequence
- DNA Mutational Analysis
- DNA Transposable Elements
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Genetic Complementation Test
- Molecular Sequence Data
- Novobiocin
- Topoisomerase II Inhibitors
- Transcription, Genetic