Article
Ultraviolet light, mitomycin C and nitrous acid induce genetic instability in Streptomyces ambofaciens ATCC23877.
Mutation research - 1 Jun 1993
Volff J N, Vandewiele D, Simonet J M, Decaris B
Abstract excerpt
In Streptomyces ambofaciens ATCC23877, pigment-negative (Pig-) mutants occur at high frequency (about 0.7 x 10(-2)) in the progenies of wild-type colonies. Furthermore, the offspring of these Pig- mutants can either be phenotypically homogeneous or hypervariable (with no preponderant phenotype). Pig- mutants can also lack antibiotic production and present aerial mycelium deficiency, auxotrophy for arginine,...
Topics
- Gene Rearrangement
- Genes, Bacterial
- Mitomycin
- Mutation
- Nitrous Acid
- SOS Response, Genetics
- Streptomyces
- Ultraviolet Rays