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Article

Streptomyces genes involved in biosynthesis of the peptide antibiotic valinomycin.

Journal of bacteriology - 1 Jun 1990

Perkins J B, Guterman S K, Howitt C L, Williams V E, Pero J

Abstract excerpt

We have identified genes from Streptomyces levoris A-9 involved in the biosynthesis of the peptide antibiotic valinomycin. Two segments of chromosomal DNA were recovered from genomic libraries, constructed by using the low-copy-number plasmid pIJ922, by complementation of valinomycin-deficient (vlm) mutants of S. levoris A-9. One set of plasmids restored valinomycin production to only one mutant, that carrying...

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Identifiers

PMID: 2345137
DOI: 10.1128/jb.172.6.3108-3116.1990
PMCID: PMC209114

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