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Article

Streptomyces genes involved in biosynthesis of the peptide antibiotic valinomycin.

Journal of bacteriology - 1 Jun 1990

Perkins J B, Guterman S K, Howitt C L, Williams V E, Pero J

Abstract excerpt

We have identified genes from Streptomyces levoris A-9 involved in the biosynthesis of the peptide antibiotic valinomycin. Two segments of chromosomal DNA were recovered from genomic libraries, constructed by using the low-copy-number plasmid pIJ922, by complementation of valinomycin-deficient (vlm) mutants of S. levoris A-9. One set of plasmids restored valinomycin production to only one mutant, that carrying...

Topics

Alleles
Chromosome Mapping
Cloning, Molecular
DNA, Bacterial
Genes, Bacterial
Sequence Homology, Nucleic Acid
Streptomyces
Valinomycin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2345137
DOI: 10.1128/jb.172.6.3108-3116.1990
PMCID: PMC209114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2345137-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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