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Metalloproteins and phytochelatin synthase may confer protection against zinc oxide nanoparticle induced toxicity in Caenorhabditis elegans.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Mar 2014

Polak Natasa, Read Daniel S, Jurkschat Kerstin, Matzke Marianne, Kelly Frank J, Spurgeon David J, Stürzenbaum Stephen R

Abstract excerpt

Zinc oxide nanoparticles (ZnONPs) are used in large quantities by the cosmetic, food and textile industries. Here we exposed Caenorhabditis elegans wild-type and a metal sensitive triple knockout mutant (mtl-1;mtl-2;pcs-1) to ZnONPs (0-50mg/L) to study strain and exposure specific effects on transcription, reactive oxygen species generation, the biomolecular phenotype (measured by Raman microspectroscopy) and key...

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Identifiers

PMID: 24333255
DOI: 10.1016/j.cbpc.2013.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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