Article
Aluminium exposure disrupts elemental homeostasis in Caenorhabditis elegans.
Metallomics : integrated biometal science - 1 May 2012
Page Kathryn E, White Keith N, McCrohan Catherine R, Killilea David W, Lithgow Gordon J
Abstract excerpt
Aluminium (Al) is highly abundant in the environment and can elicit a variety of toxic responses in biological systems. Here we characterize the effects of Al on Caenorhabditis elegans by identifying phenotypic abnormalities and disruption in whole-body metal homeostasis (metallostasis) following Al exposure in food. Widespread changes to the elemental content of adult nematodes were observed when chronically...
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