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Article

Aluminium exposure disrupts elemental homeostasis in Caenorhabditis elegans.

Metallomics : integrated biometal science - 1 May 2012

Page Kathryn E, White Keith N, McCrohan Catherine R, Killilea David W, Lithgow Gordon J

Abstract excerpt

Aluminium (Al) is highly abundant in the environment and can elicit a variety of toxic responses in biological systems. Here we characterize the effects of Al on Caenorhabditis elegans by identifying phenotypic abnormalities and disruption in whole-body metal homeostasis (metallostasis) following Al exposure in food. Widespread changes to the elemental content of adult nematodes were observed when chronically...

Topics

Aluminum
Animals
Body Size
Caenorhabditis elegans
Environmental Exposure
Female
Fertility
Homeostasis
Larva
Longevity
Male
Metals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Survival Analysis

Vulva

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Identifiers

PMID: 22534883
DOI: 10.1039/c2mt00146b
PMCID: PMC3589999

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