Article
Proliferative response of CD4+ T cells and hepatitis B virus clearance in chronic hepatitis with or without hepatitis B e-minus hepatitis B virus mutants.
Hepatology (Baltimore, Md.) - 1 Jul 1995
Löhr H F, Weber W, Schlaak J, Goergen B, Meyer zum Buschenfelde K H, Gerken G
Abstract excerpt
To assess the significance of cell-mediated immunity, T cells were derived from the peripheral blood and liver tissue of hepatitis B virus (HBV)-infected patients and controls. The analysis of the 3H-thymidine-uptake in response to a panel of recombinant HBV antigens revealed that peripheral bloo...
Topics
- CD4-Positive T-Lymphocytes
- Cell Division
- Chronic Disease
- Hepatitis B
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Interferon-alpha
- Mutation