Article
Three modified nucleosides present in the anticodon stem and loop influence the in vivo aa-tRNA selection in a tRNA-dependent manner.
Journal of molecular biology - 15 Aug 1997
Li J, Esberg B, Curran J F, Björk G R
Abstract excerpt
In Salmonella typhimurium seven tRNA species specific for leucine, proline and arginine have 1-methylguanosine (m1G) next to and 3' of the anticodon (position 37 of tRNA), five tRNA species specific for phenylalanine, serine, tyrosine, cysteine and tryptophan have 2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine (ms2io6A) in the same position of the tRNA, and four tRNA species, specific for leucine and proline,...
Topics
- Anticodon
- Base Sequence
- Binding Sites
- Codon
- Frameshift Mutation
- Genotype
- Guanosine
- Guanosine Triphosphate
- Models, Structural
- Nucleic Acid Conformation
- Peptide Elongation Factor Tu
- RNA, Bacterial
- RNA, Messenger
- RNA, Transfer, Amino Acyl