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Article

Allelic losses on chromosome band 11q13 in aldosterone-producing adrenal tumors.

Genes, chromosomes & cancer - 1 Jan 1995

Iida A, Blake K, Tunny T, Klemm S, Stowasser M, Hayward N, Gordon R, Nakamura Y, Imai T

Abstract excerpt

We examined loss of heterozygosity (LOH) in 14 aldosterone-producing adrenal tumors, with six linearly ordered restriction fragment length polymorphism (RFLP) markers that map within a 12-cM region containing the MEN1 locus on 11q13. Among 11 tumors that were informative for at least one marker, five showed LOH at one or more loci, and two distinct regions of deletion were identified. The proximal region...

Topics

Adrenal Gland Neoplasms
Aldosterone
Alleles
Chromosome Banding
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 11
DNA, Neoplasm
Heterozygote
Humans
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7534116
DOI: 10.1002/gcc.2870120114

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7534116-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Allelic losses on chromosome band 11q13 in aldosterone-producing adrenal tumors.PMID 7534116Read ↗

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