Article
Genetic predisposition of autoimmune disease and B-cell chronic lymphocytic leukemia (B-CLL).
The Tohoku journal of experimental medicine - 1 May 1994
Shirai T
Abstract excerpt
Autoimmune disease is a polygenic disease in which various genetic factors play crucial roles. The familial clustering and the association of HLA haplotypes have been well-recognized. There is a close association between chronic lymphocytic leukemia (CLL) and autoimmune disease. Like autoimmune diseases, CLL is the type of leukemia most often occurring among close relatives. The patients with CLL frequently share...
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