Article
Causation of chronic lymphocytic leukemia--insights from familial disease.
Leukemia research - 1 Oct 2003
Houlston Richard S, Sellick Gabrielle, Yuille Martin, Matutes Estella, Catovsky Daniel
Abstract excerpt
In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review...
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