Article
Contribution of transplantations to the understanding of the role of the PLP gene.
Neurochemical research - 1 Aug 1994
Lachapelle F, Gumpel M, Baumann N
Abstract excerpt
We present an overview of the results obtained in a cross-transplantation system using respectively controls, jimpy (jp), and shiverer mutant mice as donors and recipients. Homochronic transplantations (O days into O days) demonstrated that jp environment is non-toxic for non-jp cells and that, contrary to in vitro, jp oligodendrocytes phenotype cannot be modified by environmental factors at this age....
Topics
- Animals
- Brain Tissue Transplantation
- Fetal Tissue Transplantation
- Mice
- Mice, Jimpy
- Mice, Neurologic Mutants
- Myelin Proteins
- Myelin Proteolipid Protein
- Oligodendroglia
- Phenotype
- Tissue Donors