Article
Oligodendrocytes of the jimpy phenotype can be partially restored by environmental factors in vivo.
Journal of neuroscience research - 1 Jun 1991
Lachapelle F, Lapie P, Campagnoni A T, Gumpel M
Abstract excerpt
Cross-transplantations of neural tissue between jimpy (jp) shiverer (shi) and normal mice have been performed under heterochronic conditions. In all series, fragments of E14-E15 embryonic neural tissue from the different donors have been transplanted into newborn host brain in order to study environmental influences by differentiated tissue on transplanted embryonic cell lines. Large patches of proteolipid...
Topics
- Animals
- Animals, Newborn
- Brain
- Brain Tissue Transplantation
- Mice
- Mice, Inbred C3H
- Mice, Jimpy
- Mice, Neurologic Mutants
- Oligodendroglia
- Phenotype
- Telencephalon
