Article
Rumpshaker behaves like juvenile-lethal Plp mutations when combined with shiverer in double mutant mice.
Developmental neuroscience - 1 Jan 2001
Billings-Gagliardi S, Nunnari J J, Wolf M K
Abstract excerpt
The phenotypes of double mutant mice whose genomes are homozygous for an Mbp (myelin basic protein) mutation and hemizygous for a juvenile-lethal Plp (proteolipid protein) mutation were compared in earlier studies. The results suggested that the shiverer Mpb mutation might have some unexplained ability to partially rescue oligodendrocytes (OLs) from the 'death sentence' that is imposed by the Plp mutations....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.