Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Post-irradiation DNA synthesis inhibition and G2 phase delay in radiosensitive body cells from non-Hodgkin's lymphoma patients: an indication of cell cycle defects.

Mutation research - 1 Dec 1994

Hannan M A, Kunhi M, Einspenner M, Khan B A, al-Sedairy S

Abstract excerpt

In the present study, both post-irradiation DNA synthesis and G2 phase accumulation were analyzed in lymphoblastoid cell lines (LCLs) and fibroblast cell strains derived from (Saudi) patients with non-Hodgkin's lymphoma (NHL), ataxia telangiectasia (AT), AT heterozygotes and normal subjects. A comparison of the percent DNA synthesis inhibition (assayed by 3H-thymidine uptake 30 min after irradiation), and a 24 h...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Survival
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Fibroblasts

Share to Genetic Predisposition to Disease

Share to Heterozygote

Share to Homozygote

Share to Lymphocytes

Source

Identifiers

PMID: 7526192
DOI: 10.1016/0027-5107(94)90185-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Post-irradiation DNA synthesis inhibition and G2 phase delay in radiosensitive body cells from non-Hodgkin's lymphoma patients: an indication of cell cycle defects.PMID 7526192Read ↗

Alterations in p53 do not correlate with radioresistant DNA synthesis.Semantic proximity Read ↗

Activation of an ataxia telangiectasia mutation-dependent intra-S-phase checkpoint by anti-tumour drugs in HL-60 and human lymphoblastoid cells.Semantic proximity Read ↗

Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene.Semantic proximity Read ↗

DNA damage-associated dysregulation of the cell cycle and apoptosis control in cells with germ-line p53 mutation.Semantic proximity Read ↗

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.Semantic proximity Read ↗

Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.Semantic proximity Read ↗

Assessment of targeted and non-targeted responses in cells deficient in ATM function following exposure to low and high dose X-rays.Semantic proximity Read ↗

Radioprotective effect of amifostine on cells from cancer prone patients and healthy individuals studied by the G2 and PCC assays.Semantic proximity Read ↗

Lack of effect of inhibitors of DNA synthesis/repair on the ionizing radiation-induced chromosomal damage in G2 stage of ataxia telangiectasia cells.Semantic proximity Read ↗

Variation in radiation-induced apoptosis in ataxia telangiectasia lymphoblastoid cell lines.Semantic proximity Read ↗

Cytosine arabinoside enhancement of gamma irradiation induced mutations in human T-lymphocytes.Semantic proximity Read ↗

Mutagen sensitivity of human lymphoblastoid cells with a BRCA1 mutation in comparison to ataxia telangiectasia heterozygote cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.