Article
Post-irradiation DNA synthesis inhibition and G2 phase delay in radiosensitive body cells from non-Hodgkin's lymphoma patients: an indication of cell cycle defects.
Mutation research - 1 Dec 1994
Hannan M A, Kunhi M, Einspenner M, Khan B A, al-Sedairy S
Abstract excerpt
In the present study, both post-irradiation DNA synthesis and G2 phase accumulation were analyzed in lymphoblastoid cell lines (LCLs) and fibroblast cell strains derived from (Saudi) patients with non-Hodgkin's lymphoma (NHL), ataxia telangiectasia (AT), AT heterozygotes and normal subjects. A co...
Topics
- Ataxia Telangiectasia
- Cell Line, Transformed
- Cell Survival
- DNA
- DNA Replication
- Fibroblasts
- G1 Phase
- G2 Phase
- Gamma Rays
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Lymphocytes
- Lymphoma, Non-Hodgkin
- Radiation Tolerance
- Statistics, Nonparametric