Article
Variation in radiation-induced apoptosis in ataxia telangiectasia lymphoblastoid cell lines.
International journal of radiation biology - 1 Mar 2003
Fernet M, Angele S, Dörk T, Hall J
Abstract excerpt
PURPOSE: To investigate and compare the ability of Epstein-Barr virus-transformed lymphoblastoid cell lines (LCL) from healthy individuals (normals) and ataxia telangiectasia (A-T) patients to undergo apoptosis after exposure to ionizing radiation. MATERIALS AND METHODS: Four normal and eight A-T LCL were exposed to doses of up to 20 Gy ionizing radiation. Apoptosis induction was studied 24 h after irradiation...
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