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Article

Bacterial mutagenicity assays: test methods.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Gatehouse David

Abstract excerpt

The most widely used assays for detecting chemically induced gene mutations are those employing bacteria. The plate incorporation assay using various Salmonella typhimurium LT2 and E. coli WP2 strains is a short-term bacterial reverse mutation assay specifically designed to detect a wide range of chemical substances capable of causing DNA damage leading to gene mutations. The test is used worldwide as an initial...

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PMID: 22147566
DOI: 10.1007/978-1-61779-421-6_2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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