Article
Mouse alpha-fetoprotein gene 5' regulatory elements are required for postnatal regulation by raf and Rif.
Molecular and cellular biology - 1 Oct 1994
Spear B T
Abstract excerpt
The mouse alpha-fetoprotein (AFP) gene is expressed at high levels in the yolk sac and fetal liver and at low levels in the fetal gut. AFP synthesis decreases dramatically shortly after birth to low levels that are maintained in the adult liver and gut. AFP expression can be reactivated in the ad...
Topics
- Alleles
- Animals
- Animals, Newborn
- Embryo, Mammalian
- Gene Expression Regulation
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Transgenic
- Models, Genetic
- Oncogene Proteins v-raf
- Regulatory Sequences, Nucleic Acid
- Retroviridae Proteins, Oncogenic
- Trans-Activators
- alpha-Fetoproteins