Article
Quantitative gene expression analysis reveals transition of fetal liver progenitor cells to mature hepatocytes after transplantation in uPA/RAG-2 mice.
The American journal of pathology - 1 Jan 2003
Cantz Tobias, Zuckerman David M, Burda Martin R, Dandri Maura, Göricke Bettina, Thalhammer Stefan, Heckl Wolfgang M, Manns Michael P, Petersen Jörg, Ott Michael
Abstract excerpt
Therapies for liver diseases with stem and progenitor cells will require a detailed knowledge of the molecular mechanisms driving the in vivo differentiation process toward adult hepatic tissue. We applied quantitative gene expression methods to analyze the differentiation process of fetal liver progenitor cells after transplantation into an animal model of liver regeneration. Enhanced green fluorescent protein...
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