Article
Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin.
The Journal of cell biology - 1 Oct 1994
Takahashi K, Folmer J, Coulombe P A
Abstract excerpt
Injury to epidermis and other stratified epithelia triggers profound but transient changes in the pattern of keratin expression. In postmitotic cells located at the wound edge, a strong induction of K6, K16, and K17 synthesis occurs at the expense of the keratins produced under the normal situati...
Topics
- Acantholysis
- Amino Acid Sequence
- Animals
- Cell Adhesion
- Cytoskeleton
- Desmosomes
- Epidermis
- Female
- Gene Expression Regulation
- Hair
- Humans
- Keratinocytes
- Keratins
- Male
- Mice
- Mice, Transgenic
- Microscopy, Electron
- Molecular Sequence Data