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Article

Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin.

Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000

Coulombe P A, Bravo N S, Paladini R D, Nguyen D, Takahashi K

Abstract excerpt

Human cytokeratin 16 (K16; 48 kDa) is constitutively expressed in postmitotic keratinocytes in a variety of stratified epithelial tissues, but it is best known for the marked enhancement of its expression in stratified squamous epithelia showing hyperproliferation or abnormal differentiation. Of...

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Epithelium
Gene Expression Regulation
Keratins
Mice
Mice, Transgenic
Phenotype

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Recombinant Proteins

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Identifiers

PMID: 8714680
DOI: 10.1139/o95-067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8714680-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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