Article
Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000
Coulombe P A, Bravo N S, Paladini R D, Nguyen D, Takahashi K
Abstract excerpt
Human cytokeratin 16 (K16; 48 kDa) is constitutively expressed in postmitotic keratinocytes in a variety of stratified epithelial tissues, but it is best known for the marked enhancement of its expression in stratified squamous epithelia showing hyperproliferation or abnormal differentiation. Of particular interest to us, K16 is strongly induced at the wound edge after injury to the epidermis, and its...
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