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Article

Forced Expression of Keratin 16 Alters the Adhesion, Differentiation, and Migration of Mouse Skin Keratinocytes

1 Oct 2000

Abstract excerpt

Injury to the skin results in an induction of keratins K6, K16, and K17 concomitant with activation of keratinocytes for reepithelialization. Forced expression of human K16 in skin epithelia of transgenic mice causes a phenotype that mimics several aspects of keratinocyte activation. Two types of transgenic keratinocytes, with forced expression of either human K16 or a K16-C14 chimeric cDNA, were analyzed in...

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Cellular Mechanics and Interactions
Hair Growth and Disorders
Skin and Cellular Biology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11029038
DOI: 10.1091/mbc.11.10.3315

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Forced Expression of Keratin 16 Alters the Adhesion, Differentiation, and Migration of Mouse Skin KeratinocytesPMID 11029038Read ↗

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The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16Semantic proximity Read ↗

Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.Semantic proximity Read ↗

In vitro characteristics of early epidermal progenitors isolated from keratin 14 (K14)-deficient mice: Insights into the role of keratin 17 in mouse keratinocytesSemantic proximity Read ↗

Epidermal growth factor and transforming growth factor alpha specifically induce the activation- and hyperproliferation-associated keratins 6 and 16.Semantic proximity Read ↗

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