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Article

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice.

Journal of virology - 1 Jul 1994

Arbeit J M, Münger K, Howley P M, Hanahan D

Abstract excerpt

To model human papillomavirus-induced neoplastic progression, expression of the early region of human papillomavirus type 16 (HPV16) was targeted to the basal cells of the squamous epithelium in transgenic mice, using a human keratin 14 (K14) enhancer/promoter. Twenty-one transgenic founder mice were produced, and eight lines carrying either wild-type or mutant HPV16 early regions that did not express the E1 or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7515971
DOI: 10.1128/JVI.68.7.4358-4368.1994
PMCID: PMC236359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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