Article
Productive re-arrangement at both alleles of the T-cell receptor beta-chain locus in CD4 T-cell clones specific for influenza haemagglutinin.
Immunology - 1 Apr 1994
Smith C A, Graham C M, Thomas D B
Abstract excerpt
T-cell receptor (TcR) beta-chain usage, and VDJ junctional region sequences thereof in a panel of CD4+ T-cell clones Ad-, or Ak- or Ek-restricted for major antigenic sites of influenza haemagglutinin (H3 subtype), were investigated. Direct sequencing of cDNA, obtained by polymerase chain reaction...
Topics
- Alleles
- Animals
- Base Sequence
- CD4-Positive T-Lymphocytes
- Clone Cells
- DNA, Viral
- Epitopes
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Hemagglutinin Glycoproteins, Influenza Virus
- Hemagglutinins, Viral
- Mice
