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Article

V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 1990

Clarke S H, Staudt L M, Kavaler J, Schwartz D, Gerhard W U, Weigert M G

Abstract excerpt

Most (80 to 90%) primary antibodies specific for the Sb site of influenza virus (A/PR/8/34) hemagglutinin share an Id (designated C4). Secondary antihemagglutinin(Sb) antibodies also exhibit the C4 Id although less frequently (10 to 15%). We have analyzed the V region nucleotide sequences of primary and secondary antibodies with the C4 Id. Primary C4 antibodies are encoded by the same Vk gene, belonging to the...

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PMID: 2108213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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